Study focus area




Any discontinuation of antiretroviral therapy (ART) can lead to virologic rebound and increased risk of HIV progression. Vulnerable situations represent a major risk to the continuum of care cascade. The OPTICARE program is a multidisciplinary support program response dedicated to patients either lost to follow up or in highly frail situation that offers an individualized care management to optimize care and control of viral replication.

Doctress without stethoscope


Approximately 400 patients who represented an estimated 10% of vulnerable patients in Pitié-Salpêtrière Hospital were screened for the OPTICARE program. The first 120 eligible patients were enrolled into this retention in care program. Following the enrolment phase, a one year follow up for each patient will be observed. Study methodology includes analysis of a software system enabling monitoring of medical files for each HIV positive patient and questionnaires with stakeholders. The impact of OPTICARE on ART compliance, clinical, immunological and virological outcomes, and patient social and psychologic status will be assessed.

Primary objectives

  • Improve number of vulnerable patients entering care (UNAIDS/Second 90% goal)
  • Improve drive treatment success (UNAIDS/Third 90% goal) within a one-year period


 Prof. Christine Katlama

 Dr. Sophie Seang


Pitié-Salpêtrière Hospital Infectious Disease Department




Sep 2018 – Dec 2022


Retention in Care and Adherence

Key study materials

ViiV study lead and contact

Duncan Short

Director of Global Implementation Science




The RELAPP study is focused upon developing an algorithm for general practitioners in Italy to identify earlier those at risk of HIV.


As part of this study, health workers at the Hospital in non-HIV-Infectious Diseases areas and local NGO are trained to identify Chemsex and HIV-STD signs and symptoms, in order to increase diagnostic screenings of this high-risk population.


This study investigates barriers and facilitators specifically among foreign and US born Spanish and English-speaking Latino MSM.

Our partnerships

Our partnerships

We are proud to partner with multiple organizations that work to prevent HIV and improve the lives of people who live with HIV.

Find out more

NP-GBL-HVU-WCNT- 210043 | March 2022

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