Medical Education - ViiV HC CALL FOR PROPOSAL

Strategic priorities

• Optimize HIV care beyond the viral control
  • Therapeutic objectives and new outcomes for long-term management of HIV infection: the role of PROMs and PREMs as new key outcomes
  • The role of “medication burden” and “deprescribing” in chronic HIV management
  • What are the guideline recommendations for selection of effective and friendly ARV regimen (durable efficacy and low long-term toxicities) in different HIV populations and which classes drive treatment choice
  • Why, When & How switch treatment in HIV virosuppressed pts
  • ARVs and disease metabolic impact, long term metabolic toxicities, weight gain in PLWH.

• Role of core agents for best regimens across all appropriate patient types
  • What are the recommendations for selection of core agent in different regimens; specifically:
    • What is the impact of boosting
    • What is the significance of barrier to resistance of the regimen.

• Managing patients with complex co-morbidities and/or those under represented in clinical trials
  • What are the guidelines for treatment of co-infected patients (HCV/HBV, TB) and what data are available
  • Considerations for management of women, adolescents, children, aging patients, late presenters and/or high viral load patients, HTE (Highly Treatment Experienced) pts

• Evolving treatment paradigms
  • What is current research focusing on? Is there a role for changing approaches to ARV combinations (including 2DR, novel delivery methods, new MoA)
  • Very early treatment in new HIV diagnosis: same day treatment vs early personalised treatment
  • HIV treatment in a aging population: comorbidities, polipharmacy, deprescribing geriatric approach
  • How to treat MDR and HTE patients

• Other strategic areas of interest for ViiV include:
  • Cascade of care
  • Remission
  • Cure
  • Prevention
  • Management of virologically failing patient

• Other strategic areas of interest for ViiV Italy include:
  • Diagnostics and virology
  • Biology and Pharmacology of ARVs
  • Immunology in HIV
  • Health Outcome Research in HIV
  • Health Economics of HIV management
  • Methodology in Observational and clinical studies in HIV
  • Methodology of Health Technology Assessment for HIV treatment
    

10th February 2021